Agarikon was used by the Ancient Greeks to treat tuberculosis according to the writings of Pedanius Dioscorides in 65 AD, and by some indigenous people to treat smallpox. The presence of Agarikon at burial sites may indicate that its use was once widespread.

Mycologist Paul Stamets has performed numerous investigations of the biological activities of Agarikon, which have demonstrated antiviral activity against a range of viruses in vitro. This activity has been specifically observed against pox family viruses, HSV-1 and HSV-2, Influenza A, Influenza B, and Mycobacterium tuberculosis in vitro. Other researchers have identified novel chlorinated coumarins in the organism which demonstrated notably low minimum inhibitory concentrations against the Mycobacterium tuberculosis complex.

Black Pepper essential oil is high in monoterpenes and sesquiterpenes, which are natural chemicals known for their antioxidant activity. A constituent in black pepper, piperine, protects against oxidative damage by inhibiting free radicals and reactive oxygen species, as well as positively influencing antioxidant enzymes.

Research published in Applied Microbiology and Biotechnology found that black pepper extract contains anti-virulence properties, meaning it targets bacterial virulence without affecting cell viability, making drug resistance less likely. The study showed that black pepper inhibited Staphylococcus aureus biofilm formation and “almost abolished” the hemolytic (destruction of red blood cells) activity of S. aureus bacteria.

Cardamom essential oil is from the ginger family and has vitamins A, B, and C, all of which can enrich your skin. For instance, cardamom has shown to improve circulation due to its levels of vitamin C, plus it contains antioxidants and infection fighting properties that can increase the recovery time of blemishes. The skin benefits of cardamom can be attributed to its antibacterial and antioxidant properties. The essential oil can help treat skin allergies and improve skin complexion.

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